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Claims

As of snapshot 27745 under ledger-default@0.3.0.

ClaimTypeAssessmentScoreReview checksReferences
In experimental renal fibrosis, SRPX2 interacted with IRP1 and disrupted iron-regulatory signaling, and iron dextran supplementation alleviated UUO-induced renal fibrosis. CAUSAL Supported 0.9601 1 of 4 103
SRPX2 expression was elevated in CKD patient kidney and serum samples and in experimental renal-fibrosis models, while global or tubular-epithelial deletion of Srpx2 attenuated kidney injury and fibrosis in mice. CAUSAL Supported 0.9601 1 of 4 107