Claims
| Claim | Type | Assessment | Score | Review checks | References |
|---|---|---|---|---|---|
| The combinatorial relationships among regulatory motifs were largely species-specific, and models trained on individual cell types within a family lost cross-species predictive power, indicating rapidly evolving cell-type regulatory syntax. | COMPARATIVE | Supported | 0.9955 | 1 of 4 | 98 |
| Across flatworms and vertebrates, hundreds of accessibility-dictating DNA motifs formed conserved vocabularies associated with particular cell-type families, and models trained in one species could predict family-level chromatin accessibility in distant species. | COMPARATIVE | Supported | 0.9955 | 1 of 4 | 112 |