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Claims

As of snapshot 27745 under ledger-default@0.3.0.

ClaimTypeAssessmentScoreReview checksReferences
In cell-based, reconstituted-translation, and single-molecule experiments, N1-methylpseudouridine increased +1 ribosomal frameshifting at UUUC motifs in therapeutic mRNAs, while synonymous UUCC or UUUU substitutions eliminated the effect. QUANTITATIVE Supported 0.9561 1 of 4 149