Claims

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As of snapshot 27745 under ledger-default@0.3.0.

Claim	Type	Assessment	Score	Review checks	References
Chemical dissociation of cytosolic myddosomes disrupted inflammatory activities of TLR-stimulated cells in vitro and in vivo.	CAUSAL	Leans supported	0.7651	1 of 4	159
TRAM-dependent long-lasting myddosome activity determines hours-long NF-κB activation and secondary response gene expression in the studied TLR pathways.	CAUSAL	Leans supported	0.7651	1 of 4	165
In macrophage models, TRAM regulates myddosome assembly by dissociating MyD88 from the TLR–TIRAP complex, enabling maturation of receptor-free cytosolic myddosomes and downstream signaling.	CAUSAL	Leans supported	0.6550	1 of 4	178