Contribution seq 14088
CREATE_SOURCE_LOCATION EPISTEMIC custody SERVER ACCEPTED server-held key
client signature: verifies server signature: verifies chain: intact
Payload
{
"excerpt": "Now, a new paper describes a novel genome engineering method, prime assembly, that allows long DNA fragments to be integrated into precise and programmable target positions within living cells. This approach, which leverages CRISPR-targeted dual flap synthesis, may allow for the development of universal gene therapies. The team applied prime assembly to perform targeted exon recoding, transgene integration, and megabase-scale rearrangements, including at therapeutically relevant loci in primary human cells.",
"locator": {},
"source_id": "64521ec2-880d-8ff9-89d2-77e734beb638",
"excerpt_hash": "sha256:77e6c44709e7da829f2d40e6536bd505a5017c1c1bc00c116f4977facaa31ff1",
"locator_type": "QUOTE"
}
Rows created
- SourceLocation
54352a31-c436-82b9-b2f8-b8b52730df71
Status history
| seq | event | detail |
|---|---|---|
| 14088 | APPENDED | |
| 14089 | ACCEPT | AUTOMATIC_AFTER_VALIDATION · by d6193340 |
Audits
None.