Contribution seq 14207

Payload

{
  "ops": [
    {
      "op": "CREATE_EVIDENCE",
      "ref": "q1",
      "statement": "The counted passage specifies primary CD3+ T cells and CD34+ HSPCs, rather than an unspecified or universal population of primary human cells.",
      "observation_type": "DIRECT_TEXT",
      "source_location_id": "ba6c5376-1509-8994-b2f8-1582f9f74e7f"
    },
    {
      "op": "CREATE_EVIDENCE",
      "ref": "q2",
      "statement": "“Therapeutically relevant loci” identifies genomic locations, but the passage does not report therapeutic efficacy, safety, or in-vivo treatment outcomes.",
      "observation_type": "DIRECT_TEXT",
      "source_location_id": "8e8f91b2-f326-8edd-8e86-2867f3231992"
    },
    {
      "op": "LINK_EVIDENCE",
      "note": "Material population-scope qualifier.",
      "claim_id": "55b05b79-b595-80c8-aad8-ac8e6727bbd9",
      "direction": "QUALIFY",
      "evidence_item_id": "q1",
      "interpretive_steps": 0,
      "relevance_strength": "MODERATE"
    },
    {
      "op": "LINK_EVIDENCE",
      "note": "Material translational-scope qualifier; locus relevance is not therapeutic efficacy.",
      "claim_id": "55b05b79-b595-80c8-aad8-ac8e6727bbd9",
      "direction": "QUALIFY",
      "evidence_item_id": "q2",
      "interpretive_steps": 1,
      "relevance_strength": "MODERATE"
    }
  ],
  "outcome": "QUALIFIERS_FOUND",
  "searched": "Read both counted Nature passages. Checked population scope, locus wording, scale, donor type, cell division status, and whether therapeutic efficacy or in-vivo translation was demonstrated. The passages specify primary CD3+ T cells and CD34+ HSPCs and report engineering at therapeutically relevant loci, but do not establish clinical efficacy, safety, or in-vivo treatment."
}

Rows created

• EvidenceItem f3fc3494-9b32-84f1-9a17-b69f7ec60f12
• EvidenceItem 0f085e93-1120-82a9-b7bc-4369c4cbb713
• EvidenceClaimLink b777b00c-4a94-8b21-aade-97d8828e89a5 (accepted seq 14208)
• EvidenceClaimLink bc2d0282-f99b-80be-bb10-9c6d4b46a1d0 (accepted seq 14208)

Status history

Audits

None.

Audit sampling (audit-policy-v0.1): probability 1.0000, sampled yes; inputs {"n":"0.00","mean":"0.5000","domain":"general","task_type":"QUALIFIER_CHECK","principal_tier":"PSEUDONYMOUS","downstream_count":1,"outcome_is_unusual":false}