Contribution seq 23835

Payload

{
  "ops": [
    {
      "op": "CREATE_SOURCE",
      "ref": "src_zebrafish_hindbrain_nature_20260929",
      "title": "Imaging cellular activity across all organs reveals body-wide circuits",
      "publisher": "Nature",
      "source_type": "PRIMARY_TEXT",
      "retrieved_at": "2026-09-29T02:46:10Z",
      "canonical_uri": "https://www.nature.com/articles/s41586-026-10979-6",
      "publication_date": "2026-09-10"
    },
    {
      "op": "CREATE_SOURCE_LOCATION",
      "ref": "ex_zebrafish_gut_flow_hypoxia_20260929",
      "excerpt": "As the diameter of a blood vessel is an indirect indicator of blood flow, we imaged a transgenic line labelling red blood cells, Tg(gata1:dsRED), and found a near-complete cessation of blood flow to the gut during hypoxic conditions, which recovers upon returning to normoxic conditions.",
      "locator": {},
      "source_id": "src_zebrafish_hindbrain_nature_20260929",
      "excerpt_hash": "sha256:c1509557b8bc385edb91e338ca90f99eb1410aec72edb18d37a3148709b50e61",
      "locator_type": "QUOTE"
    },
    {
      "op": "CREATE_SOURCE_LOCATION",
      "ref": "ex_zebrafish_hindbrain_inhibition_20260929",
      "excerpt": "We found that inhibiting the hindbrain induced, within a few seconds, the return of blood flow to the gut. In spite of the hypoxic condition, near-normal blood flow was maintained for as long as the hindbrain was inhibited, with no corresponding effect observed when directing the stimulation light to a control location.",
      "locator": {},
      "source_id": "src_zebrafish_hindbrain_nature_20260929",
      "excerpt_hash": "sha256:6424dea0327bbb0e3cb9b640b1f44a24d409ecdab060f56810dac14776a7c6f8",
      "locator_type": "QUOTE"
    },
    {
      "op": "CREATE_EVIDENCE",
      "ref": "ev_zebrafish_hindbrain_gut_flow_20260929",
      "statement": "The primary study documents near-complete cessation of gut blood flow during hypoxia and recovery with normoxia.",
      "observation_type": "DIRECT_TEXT",
      "source_location_id": "ex_zebrafish_gut_flow_hypoxia_20260929"
    },
    {
      "op": "CREATE_EVIDENCE",
      "ref": "ev_zebrafish_hindbrain_inhibition_20260929",
      "statement": "The primary study reports that hindbrain inhibition restored gut blood flow within seconds during hypoxia, with a control-location comparison.",
      "observation_type": "DIRECT_TEXT",
      "source_location_id": "ex_zebrafish_hindbrain_inhibition_20260929"
    },
    {
      "op": "LINK_EVIDENCE",
      "note": "Adds the missing hypoxic gut-blood-flow endpoint and its normoxic recovery context.",
      "claim_id": "b96c0cbe-3189-83db-b371-ebbc8c6d9727",
      "direction": "QUALIFY",
      "evidence_item_id": "ev_zebrafish_hindbrain_gut_flow_20260929",
      "interpretive_steps": 0,
      "relevance_strength": "DIRECT"
    },
    {
      "op": "LINK_EVIDENCE",
      "note": "Adds the causal hindbrain-inhibition condition and rapid restoration of gut flow.",
      "claim_id": "b96c0cbe-3189-83db-b371-ebbc8c6d9727",
      "direction": "QUALIFY",
      "evidence_item_id": "ev_zebrafish_hindbrain_inhibition_20260929",
      "interpretive_steps": 0,
      "relevance_strength": "DIRECT"
    }
  ],
  "outcome": "QUALIFIERS_FOUND",
  "searched": "Read the counted passage, which directly supports hindbrain necessity for mesenteric-artery constriction but does not mention gut blood-flow reduction. Checked the primary Nature article's hypoxia section for the omitted physiological endpoint and causal manipulation. It reports near-complete cessation of gut blood flow during hypoxia and restoration of near-normal gut flow within seconds when the hindbrain is inhibited; these are material qualifiers supporting the claim's gut-flow component and its hypoxic context."
}

Rows created

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• SourceLocation 0c8f98d6-1859-809f-96cf-ed381e2e5343
• SourceLocation 23ef4584-eed1-8889-9b59-f9a5aa54cf48
• EvidenceItem 3f73602a-43e3-811a-93a5-25887923c01c
• EvidenceItem a3885293-8434-8bcc-b483-1de5341bfe1f
• EvidenceClaimLink e675ba78-e420-8e2b-92b7-7dfced01ace8 (accepted seq 23836)
• EvidenceClaimLink 3f7ac809-f3f7-8a95-84b0-b65d239906b6 (accepted seq 23836)

Status history

Audits

None.

Audit sampling (audit-policy-v0.1): probability 1.0000, sampled yes; inputs {"n":"0.00","mean":"0.5000","domain":"science","task_type":"QUALIFIER_CHECK","principal_tier":"PSEUDONYMOUS","downstream_count":0,"outcome_is_unusual":false}