Contribution seq 24672

Payload

{
  "ops": [
    {
      "op": "CREATE_SOURCE",
      "ref": "src_science_advances_mca1_limits",
      "title": "MCA1 mechanosensitive channels enable fast communication of wound signals between lateral roots",
      "source_type": "PRIMARY_TEXT",
      "retrieved_at": "2026-09-29T03:45:25Z",
      "canonical_uri": "https://www.science.org/doi/10.1126/sciadv.aef2202"
    },
    {
      "op": "CREATE_SOURCE_LOCATION",
      "ref": "ex_mca1_not_sole_mediator",
      "excerpt": "After wounding a distant lateral root, we observed a reduced depolarization amplitude in mca1, but not in osca1 mutant (mca1: 38.2 ± 6.8%, P = 0.0075; osca1: 92.1 ± 12.4%, P > 0.999). This indicates that MCA1, but not OSCA1, channels are involved in decoding the mechanical long-distance signals from the wounding site to neighboring lateral roots. Nevertheless, mutating this channel could not completely wipe out distant wound-evoked depolarization, indicating that other channels contribute to this phenomenon. However, no difference in the amplitude and kinetics of the wound depolarization in osca1 and mca1 plants compared to wild type was observed for local wounding.",
      "locator": {},
      "source_id": "src_science_advances_mca1_limits",
      "excerpt_hash": "sha256:cd7247b060ce64dfc806b7cd6535538489f13f6b72e1e20bf796657e3e9ae628",
      "locator_type": "QUOTE"
    },
    {
      "op": "CREATE_EVIDENCE",
      "ref": "ev_mca1_not_sole_mediator",
      "statement": "The primary study qualifies MCA1 involvement: distal depolarization is reduced but not eliminated in mca1 mutants, other channels contribute, and MCA1 is not required for the local wound response.",
      "observation_type": "DIRECT_TEXT",
      "source_location_id": "ex_mca1_not_sole_mediator"
    },
    {
      "op": "LINK_EVIDENCE",
      "note": "This primary evidence documents that MCA1 contributes to distal signaling but is neither the sole mediator nor required for the local wound response.",
      "claim_id": "23148205-dbb2-80b4-ba70-74ac46e978d7",
      "direction": "QUALIFY",
      "evidence_item_id": "ev_mca1_not_sole_mediator",
      "interpretive_steps": 0,
      "relevance_strength": "STRONG"
    }
  ],
  "outcome": "FOUND"
}

Rows created

• Source f8a5d18a-4fe3-8b85-9089-48889c476a7c
• SourceLocation a1f62c3e-9887-8742-ba5c-c5109ba60b0c
• EvidenceItem b2a5a433-5cc9-863b-a4ea-809877bb76f0
• EvidenceClaimLink 86a06d68-c407-8576-9b78-4c4806638b9d (accepted seq 24673)

Status history

Audits

None.

Audit sampling (audit-policy-v0.1): probability 1.0000, sampled yes; inputs {"n":"0.00","mean":"0.5000","domain":"science","task_type":"OPPOSING_EVIDENCE_SEARCH","principal_tier":"PSEUDONYMOUS","downstream_count":0,"outcome_is_unusual":false}