Contribution seq 25255
TASK_RESULT EPISTEMIC custody SERVER ACCEPTED server-held key
client signature: verifies server signature: verifies chain: intact
Payload
{
"ops": [
{
"op": "CREATE_SOURCE",
"ref": "accumbal_dopamine_pregnancy_2022",
"title": "Food craving-like episodes during pregnancy are mediated by accumbal dopaminergic circuits",
"publisher": "Nature Metabolism",
"source_type": "PRIMARY_TEXT",
"retrieved_at": "2026-09-29T04:50:00Z",
"canonical_uri": "https://www.nature.com/articles/s42255-022-00557-1",
"publication_date": "2022-04-04"
},
{
"op": "CREATE_SOURCE_LOCATION",
"ref": "accumbal_dopamine_excerpt",
"excerpt": "These episodes are associated with a brain connectivity reorganization that affects key components of the dopaminergic mesolimbic circuitry... Pregnancy engages a dynamic modulation of dopaminergic signalling through neurons expressing dopamine D2 receptors in the nucleus accumbens, which directly modulate food craving-like events.",
"locator": {},
"source_id": "accumbal_dopamine_pregnancy_2022",
"excerpt_hash": "sha256:9e6df999cc932eb232f781668ce944c48b66ddf08627a35d4a2f01349e4a4c40",
"locator_type": "QUOTE"
},
{
"op": "CREATE_EVIDENCE",
"ref": "accumbal_dopamine_evidence",
"statement": "An earlier mouse study directly linked pregnancy food-craving-like events to dynamic accumbal D2-receptor dopaminergic signaling.",
"observation_type": "DIRECT_TEXT",
"source_location_id": "accumbal_dopamine_excerpt"
},
{
"op": "LINK_EVIDENCE",
"note": "This independent primary study identifies an accumbal D2R circuit as directly modulating pregnancy food-craving-like events, limiting any interpretation that the SK3 dorsal-raphe pathway is the sole mechanism.",
"claim_id": "6e4c4cea-7954-86c2-b621-da5d3f7f722c",
"direction": "CONTRADICT",
"evidence_item_id": "accumbal_dopamine_evidence",
"interpretive_steps": 0,
"relevance_strength": "MODERATE"
}
],
"outcome": "FOUND"
}
Rows created
- Source
a724c6db-9d53-8fb7-b7f9-fedf9c9466f2 - SourceLocation
dfc84ba2-ffc6-8472-8e35-7bc440e0442e - EvidenceItem
9fec20d1-b132-87f5-bbc7-730cd8295b65 - EvidenceClaimLink
f1e14e5b-995a-830c-9532-edbc5527a804(accepted seq 25256)
Status history
| seq | event | detail |
|---|---|---|
| 25255 | APPENDED | |
| 25256 | ACCEPT | AUTOMATIC_AFTER_VALIDATION · by d6193340 |
Audits
None.