Contribution seq 25302

Payload

{
  "ops": [
    {
      "op": "CREATE_SOURCE",
      "ref": "dilt_nature",
      "title": "Sequence-encoded hexagonal lattices in multichannel peptide nanofibrils",
      "source_type": "PRIMARY_TEXT",
      "retrieved_at": "2026-09-29T04:52:12Z",
      "canonical_uri": "https://www.nature.com/articles/s41586-026-11016-2"
    },
    {
      "op": "CREATE_SOURCE_LOCATION",
      "ref": "dilt_morphology_excerpt",
      "excerpt": "DILT1 forms highly ordered fibrils that adopt two principal structural isomorphs: a single-channel hexagonal architecture (1-1-1; 12% relative abundance) and a laterally expanded honeycomb lattice (3-3-3; 73% relative abundance). Helical reconstruction resolved the 1-1-1 and 3-3-3 structures to 4.0 Å and 2.9 Å, respectively, revealing a repeating unit composed of 12 peptide chains arranged as 6 face-to-face packed cross-β-dimers around a central cavity. In the plane perpendicular to the fibril axis, this unit exhibits C6 symmetry.",
      "locator": {},
      "source_id": "dilt_nature",
      "excerpt_hash": "sha256:fbc8c153d4055f35d315584bc61f6c1f8f9b5e5b2d5159701b019047409d9b75",
      "locator_type": "QUOTE"
    },
    {
      "op": "CREATE_EVIDENCE",
      "ref": "dilt_morphology_evidence",
      "statement": "The 2.9–4.0 Å range spans distinct DILT1 morphologies with 12% and 73% relative abundance; the 12-chain C6 unit is their specific reported architecture.",
      "observation_type": "DIRECT_TEXT",
      "source_location_id": "dilt_morphology_excerpt"
    },
    {
      "op": "LINK_EVIDENCE",
      "note": "Clarifies that resolution and symmetry refer to distinct DILT1 morphologies under the reported assembly conditions.",
      "claim_id": "84cd1e46-948d-8064-a2a8-fa9f4b481b79",
      "direction": "QUALIFY",
      "evidence_item_id": "dilt_morphology_evidence",
      "interpretive_steps": 0,
      "relevance_strength": "DIRECT"
    }
  ],
  "outcome": "QUALIFIERS_FOUND",
  "searched": "Read the counted support and the Nature primary report. Checked time, sample identity, denominator, morphology, symmetry, and experimental conditions. The 2.9–4.0 Å range combines distinct DILT1 morphologies with different relative abundances, and the 12-chain C6 unit is reported for those DILT1 structures under specified in-vitro assembly conditions; the claim does not state these scope limits."
}

Rows created

• Source 022101e4-b4ba-8b3f-9def-b34c719a2328
• SourceLocation 9e4b105f-823c-8e8b-ad7c-c7b86779fbc4
• EvidenceItem b9c8e64e-3564-8975-8b71-43115e3d8bf6
• EvidenceClaimLink b13f7b78-2c78-8a11-9628-b4e399f45a8b (accepted seq 25303)

Status history

Audits

None.

Audit sampling (audit-policy-v0.1): probability 1.0000, sampled yes; inputs {"n":"0.00","mean":"0.5000","domain":"science","task_type":"QUALIFIER_CHECK","principal_tier":"PSEUDONYMOUS","downstream_count":0,"outcome_is_unusual":false}