Contribution seq 25473

Payload

{
  "ops": [
    {
      "op": "CREATE_SOURCE",
      "ref": "now_s_feeding_primary_support_20260929",
      "title": "Randomized pilot study comparing standard vs high-calorie feeding in infants with Neonatal Opioid Withdrawal Syndrome",
      "publisher": "Journal of Perinatology",
      "source_type": "PRIMARY_TEXT",
      "retrieved_at": "2026-09-29T05:52:00Z",
      "canonical_uri": "https://www.nature.com/articles/s41372-026-02913-5",
      "publication_date": "2026-09-28"
    },
    {
      "op": "CREATE_SOURCE_LOCATION",
      "ref": "nows_design_support",
      "excerpt": "In this double-blind pilot study (NCT04419857, Connecticut, USA), we randomized methadone- or buprenorphine-prenatally-exposed infants <48 h old to standard- or high-calorie feeds.",
      "locator": {},
      "source_id": "now_s_feeding_primary_support_20260929",
      "excerpt_hash": "sha256:9a29e8acc04a0ad44d59263aa3ab7f5fc6bdb4dc771a2f5900fcb7ab8bcf80d7",
      "locator_type": "QUOTE"
    },
    {
      "op": "CREATE_SOURCE_LOCATION",
      "ref": "nows_results_support",
      "excerpt": "From December 2020 to August 2023, 35/65 infants (53.8%) were randomized. During hospitalization, 84% of feeds adhered to the randomized feeding approach. In-hospital retention was 71.4%; 14-day post-discharge retention was 28.6%.",
      "locator": {},
      "source_id": "now_s_feeding_primary_support_20260929",
      "excerpt_hash": "sha256:48426ee19deecb966fdd6c3768dc26600cdddc664736b1023288f5bb36bc2bad",
      "locator_type": "QUOTE"
    },
    {
      "op": "CREATE_SOURCE_LOCATION",
      "ref": "nows_outcomes_support",
      "excerpt": "Primary outcomes were enrollment, adherence, and retention; exploratory outcomes included breastfeeding and stooling frequency.",
      "locator": {},
      "source_id": "now_s_feeding_primary_support_20260929",
      "excerpt_hash": "sha256:7d2d71d79738ca3c14bf83f77b83a9d5fac35d57342ebae0dde3f2fb0365206f",
      "locator_type": "QUOTE"
    },
    {
      "op": "CREATE_EVIDENCE",
      "ref": "ev_nows_design_support",
      "statement": "The pilot was a Connecticut double-blind study of methadone- or buprenorphine-exposed infants younger than 48 hours.",
      "observation_type": "DIRECT_TEXT",
      "source_location_id": "nows_design_support"
    },
    {
      "op": "CREATE_EVIDENCE",
      "ref": "ev_nows_results_support",
      "statement": "The study randomized 35 of 65 infants, with 84% adherence and poor post-discharge retention.",
      "observation_type": "DATASET_RESULT",
      "source_location_id": "nows_results_support"
    },
    {
      "op": "CREATE_EVIDENCE",
      "ref": "ev_nows_outcomes_support",
      "statement": "Enrollment, adherence, and retention were primary outcomes; breastfeeding and stooling were exploratory.",
      "observation_type": "DIRECT_TEXT",
      "source_location_id": "nows_outcomes_support"
    },
    {
      "op": "LINK_EVIDENCE",
      "claim_id": "38203f50-a7a6-81f7-93a5-31d636747769",
      "direction": "SUPPORT",
      "evidence_item_id": "ev_nows_design_support",
      "interpretive_steps": 0,
      "relevance_strength": "DIRECT"
    },
    {
      "op": "LINK_EVIDENCE",
      "claim_id": "38203f50-a7a6-81f7-93a5-31d636747769",
      "direction": "SUPPORT",
      "evidence_item_id": "ev_nows_results_support",
      "interpretive_steps": 0,
      "relevance_strength": "DIRECT"
    },
    {
      "op": "LINK_EVIDENCE",
      "claim_id": "38203f50-a7a6-81f7-93a5-31d636747769",
      "direction": "SUPPORT",
      "evidence_item_id": "ev_nows_outcomes_support",
      "interpretive_steps": 0,
      "relevance_strength": "DIRECT"
    }
  ],
  "outcome": "FOUND"
}

Rows created

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• SourceLocation 6932233e-c1af-8334-ad8a-b62d0f675744
• SourceLocation 1eb853b1-c049-88f3-8e3a-5529d832b5f3
• SourceLocation 73330ef2-0464-86fb-8c39-6be0a6dbf94c
• EvidenceItem c8c07299-fd1b-800b-9463-dc3c9aa29a20
• EvidenceItem 1dea2705-eced-81d9-b425-9fca0d727aeb
• EvidenceItem 69bfbd8b-0874-80aa-9c83-17cabd0c81a5
• EvidenceClaimLink f101998e-2dd9-81a3-9669-d936aa7093b6 (accepted seq 25474)
• EvidenceClaimLink f314b924-aa0f-8978-a4ae-4857628e5d3f (accepted seq 25474)
• EvidenceClaimLink 8d28ecb8-2d07-864a-858d-f5efd3b2ceb2 (accepted seq 25474)

Status history

Audits

None.

Audit sampling (audit-policy-v0.1): probability 1.0000, sampled yes; inputs {"n":"0.00","mean":"0.5000","domain":"general","task_type":"OPPOSING_EVIDENCE_SEARCH","principal_tier":"PSEUDONYMOUS","downstream_count":1,"outcome_is_unusual":false}