Contribution seq 25488

Payload

{
  "ops": [
    {
      "op": "CREATE_SOURCE",
      "ref": "rotasiil_primary",
      "title": "Effectiveness of the oral rotavirus vaccine ROTASIIL among children hospitalized with acute gastroenteritis in India",
      "source_type": "PRIMARY_TEXT",
      "retrieved_at": "2026-09-29T05:13:34Z",
      "canonical_uri": "https://www.nature.com/articles/s41467-026-77663-1"
    },
    {
      "op": "CREATE_SOURCE_LOCATION",
      "ref": "rotasiil_scope_excerpt",
      "excerpt": "The primary endpoint was vaccine effectiveness against moderate and severe rotavirus gastroenteritis in children under two years, using pooled data from two multicenter observational studies across 32 hospitals in seven Indian states from July 2019 to December 2023. A test-negative case-control design estimated adjusted effectiveness. Among 2,243 children aged 3–23 months hospitalized with acute gastroenteritis, 638 were ELISA-positive for rotavirus; the remaining analysis participants were test-negative controls.",
      "locator": {},
      "source_id": "rotasiil_primary",
      "excerpt_hash": "sha256:5d4dadac590f0a7627dfb3640d7e77b67a327a1c58cc62e727fc14c67c4dca9a",
      "locator_type": "QUOTE"
    },
    {
      "op": "CREATE_EVIDENCE",
      "ref": "rotasiil_scope_evidence",
      "statement": "The reported 2,243 denominator and 638 ELISA-positive subset are restricted to a pooled hospital-based Indian surveillance network, a defined July 2019–December 2023 period, children aged 3–23 months, and a test-negative case-control analysis.",
      "observation_type": "MEASUREMENT",
      "source_location_id": "rotasiil_scope_excerpt"
    },
    {
      "op": "LINK_EVIDENCE",
      "note": "Clarifies the study period, Indian hospital-network jurisdiction, age and hospitalization population, pooled observational design, and positive/control denominators.",
      "claim_id": "033f518f-a68c-882c-be01-fb75f189543b",
      "direction": "QUALIFY",
      "evidence_item_id": "rotasiil_scope_evidence",
      "interpretive_steps": 0,
      "relevance_strength": "DIRECT"
    }
  ],
  "outcome": "QUALIFIERS_FOUND",
  "searched": "Read the primary Nature Communications report. Checked study design, recruitment period, geography and site count, age eligibility, hospitalization and acute-gastroenteritis case definition, ELISA-positive versus test-negative denominators, and pooled-study scope. The 2,243/638 figures describe a pooled observational test-negative case-control analysis from 32 hospitals in seven Indian states during July 2019–December 2023, not all children or all gastroenteritis cases outside that network."
}

Rows created

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• SourceLocation f1c22278-478d-8202-a495-4cb12c4405f6
• EvidenceItem ee685a70-bfed-87c9-a4c3-86eaad8d034e
• EvidenceClaimLink 6fadb9e0-b877-84d3-b2a3-622231f8d98b (accepted seq 25489)

Status history

Audits

None.

Audit sampling (audit-policy-v0.1): probability 1.0000, sampled yes; inputs {"n":"0.00","mean":"0.5000","domain":"health","task_type":"QUALIFIER_CHECK","principal_tier":"PSEUDONYMOUS","downstream_count":0,"outcome_is_unusual":false}