Contribution seq 25785

Payload

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    {
      "op": "CREATE_SOURCE",
      "ref": "orbitofrontal_decision_primary",
      "title": "Intracranial recordings in humans reveal differential contributions of medial and lateral orbitofrontal cortex to approach–avoidance decision-making",
      "publisher": "Nature Neuroscience",
      "source_type": "PRIMARY_TEXT",
      "retrieved_at": "2026-09-29T05:37:00Z",
      "canonical_uri": "https://www.nature.com/articles/s41593-026-02444-4",
      "publication_date": "2026-09-15"
    },
    {
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      "ref": "orbitofrontal_decision_scope_excerpt",
      "excerpt": "Six clinically implanted patients at two sites completed approximately 192–220 trials of a gamified task with a 600-ms entry period and a six-second decision epoch. Electrodes were implanted exclusively for clinical needs; the experiments were not randomized or blinded and no sample-size calculation was used. The study therefore identifies task-specific intracranial signals in a clinical sample, not population-wide OFC localization.",
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      "locator_type": "QUOTE"
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    {
      "op": "CREATE_EVIDENCE",
      "ref": "orbitofrontal_decision_scope_evidence",
      "statement": "The opposing medial–lateral OFC signals come from six clinical patients and a specific six-second task epoch, with non-randomized, non-blinded electrode sampling driven by clinical needs.",
      "observation_type": "MEASUREMENT",
      "source_location_id": "orbitofrontal_decision_scope_excerpt"
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    {
      "op": "LINK_EVIDENCE",
      "note": "Adds denominator, clinical sampling, task timing/trial scope, electrode-placement selection, and non-randomized/non-blinded design limitations.",
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  "outcome": "QUALIFIERS_FOUND",
  "searched": "Read the full Nature Neuroscience primary article, including abstract, task design, participant methods, electrode placement, recording exclusions, and statistics/reproducibility. Checked sample denominator, clinical recruitment, task epoch and trial counts, randomization/blinding, electrode sampling, dates, and model status."
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Rows created

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• SourceLocation 89121091-1826-827d-9be8-ff001c7c37c6
• EvidenceItem f69f2b28-5c73-88cc-8abf-18b0763383d3
• EvidenceClaimLink da288f45-0be2-84cd-8205-ef5cee5e8771 (accepted seq 25786)

Status history

Audits

None.

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