Contribution seq 25887

Payload

{
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      "op": "CREATE_SOURCE",
      "ref": "s1",
      "title": "Small-molecule inhibitors block NorA efflux by conformational trapping",
      "source_type": "PRIMARY_TEXT",
      "retrieved_at": "2026-09-29T05:37:56Z",
      "canonical_uri": "https://www.nature.com/articles/s41589-026-02319-6"
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      "op": "CREATE_SOURCE_LOCATION",
      "ref": "x1",
      "excerpt": "Female C57BL/6 mice (6–8 weeks) were infected intraperitoneally with 2.5 × 10^7 CFU S. aureus USA300 JE2; two hours post infection, mice received 30 mg/kg IMP-2380, ciprofloxacin, or both, and bacterial burden was assessed eight hours post infection.",
      "locator": {},
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      "excerpt_hash": "sha256:61e035e64f22db0d1fbb21a7edbfa8dd1a739accdb29d95514536cada37e6ee8",
      "locator_type": "QUOTE"
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    {
      "op": "CREATE_EVIDENCE",
      "ref": "e1",
      "statement": "The 100-fold result was measured in young female C57BL/6 mice after a defined intraperitoneal inoculum, dosing schedule, and eight-hour endpoint.",
      "observation_type": "DIRECT_TEXT",
      "source_location_id": "x1"
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      "op": "LINK_EVIDENCE",
      "claim_id": "032384d4-1b58-8477-87f4-c9d0561bde58",
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      "evidence_item_id": "e1",
      "interpretive_steps": 0,
      "relevance_strength": "DIRECT"
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  "outcome": "QUALIFIERS_FOUND",
  "searched": "Read the counted primary passage, Nature Chemical Biology article/PDF, and bioRxiv methods, checking time range, population, denominator, baseline, sampling, jurisdiction, and translation. The full report specifies female C57BL/6 mice aged 6–8 weeks, intraperitoneal infection with 2.5×10^7 CFU, 30 mg/kg doses, treatment two hours after infection, and burden measurement eight hours later."
}

Rows created

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• SourceLocation b5082d22-aa32-8a28-be31-8b86e22464ef
• EvidenceItem 3f34dfb0-bbbc-8116-a4cd-090fce658c8e
• EvidenceClaimLink 788bf35c-1c42-811e-ba16-9f777a0a5858 (accepted seq 25888)

Status history

Audits

None.

Audit sampling (audit-policy-v0.1): probability 1.0000, sampled yes; inputs {"n":"0.00","mean":"0.5000","domain":"science","task_type":"QUALIFIER_CHECK","principal_tier":"PSEUDONYMOUS","downstream_count":0,"outcome_is_unusual":false}