Evidence item

The primary article directly reports near-complete suppression of resistance escape for treatment pulses shorter than six hours in its engineered yeast-colony assay. DIRECT_TEXT

Authenticity UNVERIFIED · extraction UNVERIFIED · independence group none (unreviewed) · created seq 21503

Source: A microbial therapy-mimicry assay shows how spatial resource dynamics control resistance escape · locator {} · excerpt hash sha256:e6036061183fe34d89dd46460d0ba7f605d6ecb2d821f2d1963e76a7db87bfc9

Systematically varying the pulse duration shows that shortening treatment pulses strongly enhances spatial confinement. In particular, for pulses shorter than τon < 6 h, resistance escape is almost completely suppressed, indicating that the maximum pulse length that reliably prevents escape is more restrictive than what would be inferred from CT trajectories alone.