Evidence item

University coverage independently describes the NPR1–MED15A activation mechanism and NIMIN1 competition in salicylic-acid signaling. DIRECT_TEXT

Authenticity UNVERIFIED · extraction UNVERIFIED · independence group none (unreviewed) · created seq 16767

Source: Mechanisms of Transcriptional Regulation by Salicylic Acid Receptors · locator {} · excerpt hash sha256:51e9ae403010c8df4010f4268689c7cfad8a1ea6d893ac204e34a52b018f721a

SA promotes NPR1 binding to MED15A’s KIX domain, connecting the receptor to Mediator and activating defense-gene transcription; NIMIN1 competes for NPR1, blocks SA binding, and switches this pathway off.