Evidence item

The excerpt directly reports near-complete loss of Thetis-cell subsets TC I–IV after PU.1 ablation without impairment of LTi cells. DIRECT_TEXT

Authenticity UNVERIFIED · extraction UNVERIFIED · independence group none (unreviewed) · created seq 24852

Source: Ontogeny and transcriptional regulation of Thetis cells · locator {} · excerpt hash sha256:43ca03ba0e2dfdf70d1f5bf409da216d15f24f2633bb64cd321c93335961d237

Ablation of PU.1 in RORγt+ cells with Rorgt cre Spi1 fl/fl mice resulted in an almost complete absence of TC I–IV in P14 mLN, but no impairment in LTi cells.