Evidence item

The estimate comes from pooled observational test-negative case-control studies at 32 hospitals in seven Indian states during July 2019–December 2023. DIRECT_TEXT

Authenticity UNVERIFIED · extraction UNVERIFIED · independence group none (unreviewed) · created seq 25977

Source: Effectiveness of the oral rotavirus vaccine ROTASIIL among children hospitalized with acute gastroenteritis in India · locator {} · excerpt hash sha256:5a73216ab42fd44b2cfa467147dcd3c62d96a47c3aa867abac84969b8853cd2e

Primary endpoint was vaccine effectiveness (VE) against moderate and severe rotavirus gastroenteritis (RVGE) in children <2 years using pooled data from two multi-center observational studies across 32 hospitals in seven states (July 2019–December 2023). A test-negative case–control design estimated adjusted VE (aVE) for three ROTASIIL doses.