Evidence item

An independent earlier double-blind randomized feasibility study in methadone-exposed infants likewise found no significant main outcome differences between standard- and high-calorie formula, providing contextual support for the newer pilot's null findings. DIRECT_TEXT

Authenticity UNVERIFIED · extraction UNVERIFIED · independence group none (unreviewed) · created seq 19171

Source: Randomized Clinical Trial of Standard- Versus High-Calorie Formula for Methadone-Exposed Infants: A Feasibility Study · locator {} · excerpt hash sha256:da110f0b00c288188027dac03173602164bc184e554d5e7c7f9dfd9e46d55029

A total of 49 infants were randomly assigned (22 to standard- and 27 to high-calorie formula); groups had comparable demographic characteristics. Main outcomes comparing standard- to high-calorie formula groups were not significant ... There were high levels of protocol adherence, and no adverse effects were observed.