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Evidence item

The excerpt directly reports a significant 100-fold CFU reduction and three of five infections below assay detection. DIRECT_TEXT

Authenticity UNVERIFIED · extraction UNVERIFIED · independence group none (unreviewed) · created seq 24715

Source: Small-molecule inhibitors block NorA efflux by conformational trapping · locator {} · excerpt hash sha256:934556fe7cdf164a2ecef982c3657785c0e7ea99a423fab2d9ebd79897b19580

Exact excerpt
IMP-2380 in combination with ciprofloxacin caused a significant 100-fold reduction in CFU count, with infections in three of five animals being below the limit of detection of the assay.

Linked claims

ClaimDirectionRelevanceStepsCounted
561bde58SUPPORTDIRECT0yes

Audits

None.