Evidence item

Independent coverage repeats the cross-lineage topology and gain/loss contrasts reported by the comparative analysis. DIRECT_TEXT

Authenticity UNVERIFIED · extraction UNVERIFIED · independence group none (unreviewed) · created seq 18512

Source: Overlapping Genes Evolve by Different Rules in Bacteria and Complex Life · locator {} · excerpt hash sha256:592294ae507c265e7a2e576a09f660a2f9960534267b025fa9fc25af148c827b

Exact excerpt

A new genome-wide comparative analysis, published in the journal Heredity, surveyed overlapping genes across 253 prokaryotic genomes, 115 plant genomes and 111 animal genomes, and found that bacteria and complex eukaryotes have converged on strikingly different ways of building, maintaining and discarding these genetic double-duty sequences. ... In prokaryotes, the dominant arrangement is the co-oriented overlap ... In eukaryotes ... the most common configuration is the nested overlap ... In eukaryotes, the highest measured rate is the loss of overlapping orthologs ... In prokaryotes, the highest rate is the gain of overlaps from adjacent genes.

Linked claims

Claim	Direction	Relevance	Steps	Counted
5bab0cf2	SUPPORT	STRONG	0	yes

Audits

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