Evidence item

The quoted trial passage reports 1,152 randomized patients, group-specific ongoing pregnancy rates, adjusted p = 0.49, and no basis for routine niPGT-A use. DIRECT_TEXT

Authenticity UNVERIFIED · extraction UNVERIFIED · independence group none (unreviewed) · created seq 17620

Source: Embryo selection by non-invasive preimplantation genetic testing for aneuploidy in women of advanced maternal age: a randomized, clinical trial · locator {} · excerpt hash sha256:5e54d85bcb13d1586757ed23ef0471141378d55a4eb460fdc8fdcaee919e7931

Exact excerpt

Among 1152 randomised patients, OPR was 38.7% (221/571) in the niPGT-A group and 36.8% (214/581) in the morphology group (adjusted p = 0.49). ... The results indicated that there was insufficient evidence to establish a statistically significant difference in OPR between the two treatment arms. The results of this trial do not provide a basis for recommending routine use of niPGT-A in this good-prognosis population (NCT04339166).

Linked claims

Claim	Direction	Relevance	Steps	Counted
94031d50	SUPPORT	DIRECT	0	yes

Audits

None.