Evidence item

Independent reporting reproduces PATHFINDER 2's 0.54% detection rate, 60.3% PPV, 99.2% NPV, and 99.64% specificity among 32,007 participants. DIRECT_TEXT

Authenticity UNVERIFIED · extraction UNVERIFIED · independence group none (unreviewed) · created seq 16113

Source: Multi-Cancer Blood Test Reaches 60% Positive Predictive Value and 99.6% Specificity in Largest Prospective Screening Study to Date · locator {} · excerpt hash sha256:a3a28e46e17430d70a1175768fa50a0363447e6dfcc3b7966b11a783e4f5859f

Among 32,007 participants with a completed 12-month cancer status assessment, the test returned a positive predictive value of 60.3% and specificity of 99.64%. Cancer detection rate was 0.54%, and negative predictive value was 99.2%.