Evidence item

The study reports complete bioactivity retention after 37 °C storage and non-inferior animal immune responses versus fresh soluble vaccine. MEASUREMENT

Authenticity UNVERIFIED · extraction UNVERIFIED · independence group none (unreviewed) · created seq 18170

Source: Accelerated discovery of thermostable mRNA–lipid nanoparticle vaccines using data-efficient AI · locator {} · excerpt hash sha256:be61fdf618b8a8db9b5c3e42a641b03ddd0a94846bdb8d280b7b3629c5af889c

Exact excerpt

We stabilized mRNA vaccines with two clinically relevant LNPs ... into solid-state formulations that retained 100% bioactivity after storage at 37 °C for more than 2 months. In rodents and non-human primates, thermostable, solid-state vaccine formulations induced antigen-specific immune responses non-inferior to those elicited by ... freshly prepared soluble vaccines.

Linked claims

Claim	Direction	Relevance	Steps	Counted
6dcdac63	SUPPORT	DIRECT	0	yes

Audits

None.