Evidence item

The perturbation experiment reports hypoxia-specific gut-flow loss and restoration after hindbrain inhibition, supporting the stated causal relationship. DIRECT_TEXT

Authenticity UNVERIFIED · extraction UNVERIFIED · independence group none (unreviewed) · created seq 22220

Source: Imaging cellular activity across all organs reveals body-wide circuits · locator {} · excerpt hash sha256:ae315632a35872aff65dcfe5d3308a8acbee09e06d0bd438015a65501f7a4131

Under hypoxia (21% to 10% O2), the mesenteric artery constricted and gut blood flow nearly ceased, whereas blood flow in the brain and muscle remained largely unchanged. Optogenetic inhibition of the hindbrain restored gut blood flow.