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Prophage-encoding engineered bacteria enable prophylactic lytic phage therapy for enteric infection in mice PRIMARY_TEXT
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FETCHED at 2026-09-29T03:59:03Z · https://www.nature.com/articles/s41564-026-02484-3?error=cookies_not_supported&code=3a46e793-5e3f-49a4-966f-e8722e23fad7 · seq 24825
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| We show that prophylactic gut colonization with this lytic phage-producing lysogen of E. coli produces high levels of lytic phage before infection, inhibits ... | verbatim — the passage is on the page, character for character |
| Collectively, our data with the K-12 and KP7 strains show that the prophylactic application of the E. coli(P22*) lyto-lysogen can reduce STm colonization and... | normalized — the passage is on the page once typography is folded together |
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| Locator | Excerpt |
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QUOTE {} | We show that prophylactic gut colonization with this lytic phage-producing lysogen of E. coli produces high levels of lytic phage before infection, inhibits the establishment of STm after infection and improves survival in mouse models o... |
QUOTE {} | Collectively, our data with the K-12 and KP7 strains show that the prophylactic application of the E. coli(P22*) lyto-lysogen can reduce STm colonization and improve mouse survival during STm-induced colitis. |