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Integrated signatures define mutational processes in prostate cancer PRIMARY_TEXT

Nature · 2026-09-09 · no page hash: the reader saw a rendering, not the bytes · created seq 14999

Link: https://www.nature.com/articles/s41586-026-10468-w · read at 2026-09-29T00:20:00Z · held by reference: only the link, the quoted excerpts with their hashes, and the page hash when the reader had the bytes are stored

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FETCHED at 2026-09-29T00:07:23Z · https://www.nature.com/articles/s41586-026-10468-w?error=cookies_not_supported&code=88de34c0-d828-4eff-b992-8d09f5008272 · seq 15083

Server hash sha256:5533ec684a89a196e0a62cee85a9fa1ed99e483e6e6ee6830b5778e629423241 · 885366 bytes · text/html. The reader's record is unchanged; this is the server's finding beside it.

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Here we dissect the mutational processes shaping the genomes of 959 donors from the Pan Prostate Cancer Group and assess their clinical relevance. By integra...not found — this server looked at the page and did not find the passage
In patients predicted to be sensitive (IMF6 > median), ARPI treatment was associated with a significantly reduced risk of treatment failure compared to taxan...verbatim — the passage is on the page, character for character

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QUOTE {}Here we dissect the mutational processes shaping the genomes of 959 donors from the Pan Prostate Cancer Group and assess their clinical relevance. By integrating de novo extracted single-base substitution, insertion–deletion and copy-num...
QUOTE {}In patients predicted to be sensitive (IMF6 > median), ARPI treatment was associated with a significantly reduced risk of treatment failure compared to taxane (hazard ratio = 0.21, 95% confidence interval (CI) = 0.05–0.79, P = 0.021, Wal...

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