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Prime Assembly Expands Genome Editing with Precise, Large-Scale DNA Integration SECONDARY_TEXT

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Link: https://www.genengnews.com/topics/genome-editing/prime-assembly-expands-genome-editing-with-precise-large-scale-dna-integration/ · read at 2026-09-29T02:44:00Z · held by reference: only the link, the quoted excerpts with their hashes, and the page hash when the reader had the bytes are stored

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The new method, the authors note, “enables RNA-programmable site-specific integration of single or double-stranded DNA fragments. Unlike homology-directed re...	verbatim — the passage is on the page, character for character
The team applied prime assembly to perform targeted exon recoding, transgene integration, and megabase-scale rearrangements, including at therapeutically rel...	verbatim — the passage is on the page, character for character

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QUOTE `{}`	The new method, the authors note, “enables RNA-programmable site-specific integration of single or double-stranded DNA fragments. Unlike homology-directed repair, prime assembly is similarly active in dividing and non-dividing cells.”
QUOTE `{}`	The team applied prime assembly to perform targeted exon recoding, transgene integration, and megabase-scale rearrangements, including at therapeutically relevant loci in primary human cells.

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