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Identifying Key Factors Affecting mRNA-Lipid Nanoparticles Drug Product Formulation Stability PRIMARY_TEXT retrieval pending

Nanomaterials · no page hash: the reader saw a rendering, not the bytes · created seq 13885

Link: https://www.mdpi.com/2079-4991/16/4/268 · read at 2026-09-28T23:26:42Z · held by reference: only the link, the quoted excerpts with their hashes, and the page hash when the reader had the bytes are stored

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QUOTE `{}`	Formulations stored at −80 °C and −20 °C retained acceptable stability, while storage at 5 °C caused aggregation, reduced in vivo expression, and mRNA degradation. Storage at 25 °C led to complete loss of transfection within six months.

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