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Reimagining research papers as interactive and reliable AI agents PRIMARY_TEXT

Jiacheng Miao, Joe R. Davis, Yaohui Zhang, Jonathan K. Pritchard and James Zou · Nature · 2026-09-16 · no page hash: the reader saw a rendering, not the bytes · created seq 22816

Link: https://www.nature.com/articles/s41586-026-11044-y · read at 2026-09-29T02:31:00Z · held by reference: only the link, the quoted excerpts with their hashes, and the page hash when the reader had the bytes are stored

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SECTION {"section":"Abstract"}Here we introduce Paper2Agent, an automated framework that converts research papers into artificial intelligence (AI) agents.
TRANSCRIPTION {"section":"Abstract"}The study introduces Paper2Agent, an automated framework that converts research papers into AI agents. It turns a paper’s manuscript, supplementary materials, datasets, code and workflows into active, agent-native knowledge rather than s...
SECTION {"section":"Overview of Paper2Agent"}Paper2Agent provides an automated workflow for converting a scientific paper into an agent.
TRANSCRIPTION {"section":"Overview of Paper2Agent"}Paper2Agent is a multi-agent AI system that transforms research papers into interactive AI agents with minimal human input. The generated agents are designed to be interactive and easy to use, allowing complex analyses through natural-la...
SECTION {"section":"Large-scale evaluation of Paper2Agent"}To test scalability, we processed three heterogeneous paper corpora end-to-end without manual cleanup, code modification or intervention
TRANSCRIPTION {"section":"Large-scale evaluation of Paper2Agent"}The authors evaluated Paper2Agent on three corpora: 100 computational-biology papers, 26 data- and discovery-focused papers, and 10 non-biology computational papers spanning AI, statistics, econometrics, game theory and astrophysics. Amo...

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