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Single-nucleus atlas of cell-type specific genetic regulation in the human brain PRIMARY_TEXT
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FETCHED at 2026-09-29T02:37:01Z · https://www.nature.com/articles/s41588-026-02733-5?error=cookies_not_supported&code=6d96343b-dd2d-4471-bc2c-a1729918d2c4 · seq 23464
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| Here we present a comprehensive, single-nucleus multi-ancestry atlas of genetic regulation of gene expression in the human prefrontal cortex, comprising 5.6 ... | verbatim — the passage is on the page, character for character |
| Colocalization of genetic variants associated with gene regulation and disease traits uncovers novel cell type-specific genes implicated in Alzheimer’s disea... | verbatim — the passage is on the page, character for character |
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QUOTE {} | Here we present a comprehensive, single-nucleus multi-ancestry atlas of genetic regulation of gene expression in the human prefrontal cortex, comprising 5.6 million nuclei from 1,384 donors of diverse ancestries. Through multi-resolution... |
QUOTE {} | Colocalization of genetic variants associated with gene regulation and disease traits uncovers novel cell type-specific genes implicated in Alzheimer’s disease, schizophrenia and other disorders that were not detectable in bulk tissue an... |