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Massively parallel assessment of gene regulatory activity at human cortical-structure-associated variants PRIMARY_TEXT
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FETCHED at 2026-09-29T00:00:08Z · https://www.nature.com/articles/s41593-026-02454-2?error=cookies_not_supported&code=f5235591-7a49-42ca-a406-6b1b7ef1f455 · seq 14872
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| Here we implemented a massively parallel reporter assay to measure the regulatory activity of 9,092 cortical-structure-associated variants in human neural pr... | verbatim — the passage is on the page, character for character |
| We found 32 elements with higher activity because of Wnt stimulation and seven elements with higher activity in the vehicle condition, demonstrating Wnt-depe... | not found — this server looked at the page and did not find the passage |
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QUOTE {} | Here we implemented a massively parallel reporter assay to measure the regulatory activity of 9,092 cortical-structure-associated variants in human neural progenitor cells at baseline and during Wnt stimulation. We identified 918 variant... |
QUOTE {} | We found 32 elements with higher activity because of Wnt stimulation and seven elements with higher activity in the vehicle condition, demonstrating Wnt-dependent gene regulation of cortical-structure-associated elements. ... By using an... |