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One night of closed-loop auditory stimulation during sleep enhances memory consolidation in patients with Alzheimer’s Disease PRIMARY_TEXT

medRxiv · 2026-09-17 · no page hash: the reader saw a rendering, not the bytes · created seq 23352

Link: https://www.medrxiv.org/content/10.64898/2026.09.14.26360893v1 · read at 2026-09-29T05:17:00Z · held by reference: only the link, the quoted excerpts with their hashes, and the page hash when the reader had the bytes are stored

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FETCHED at 2026-09-29T05:05:59Z · https://www.medrxiv.org/content/10.64898/2026.09.14.26360893v1 · seq 25405

Server hash sha256:0731db7fe2e7b471f14fe873a979d795d8bf2e48cb94d9b9638c039d9f4481dd · 146696 bytes · text/html. The reader's record is unchanged; this is the server's finding beside it.

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We conducted a randomized, double-blind, placebo-controlled crossover trial in 37 patients with biomarker-confirmed early symptomatic AD and an amnestic clin...verbatim — the passage is on the page, character for character
CLAS significantly improved overnight word-pair consolidation (Cohen’s dz = 0.42, p = 0.04), enhanced stimulation-evoked slow-wave and fast spindle activity,...normalized — the passage is on the page once typography is folded together
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QUOTE {}We conducted a randomized, double-blind, placebo-controlled crossover trial in 37 patients with biomarker-confirmed early symptomatic AD and an amnestic clinical phenotype. We assessed the effect of one night of CLAS, compared with one n...
QUOTE {}CLAS significantly improved overnight word-pair consolidation (Cohen’s dz = 0.42, p = 0.04), enhanced stimulation-evoked slow-wave and fast spindle activity, and preserved sleep architecture and subjective sleep quality.

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