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Mechanical stress remodelling drives epithelial–mesenchymal transition in the tumour microenvironment PRIMARY_TEXT
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FETCHED at 2026-09-29T04:14:02Z · https://www.nature.com/articles/s41565-026-02282-2?error=cookies_not_supported&code=cbafdf3c-8885-474a-b3f1-0aad9e9f325b · seq 24949
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| Calibration of the stress–R2 relationship enables a quantitative measurement of local tissue stress over a physiologically relevant range of 0–15 kPa. We dem... | normalized — the passage is on the page once typography is folded together |
| Strikingly, abrupt stress increases, rather than cumulative or peak stress magnitude, determine epithelial–mesenchymal transition induction. | verbatim — the passage is on the page, character for character |
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QUOTE {} | Calibration of the stress–R2 relationship enables a quantitative measurement of local tissue stress over a physiologically relevant range of 0–15 kPa. We demonstrate the platform in tumour spheroids and mouse xenografts, enabling the non... |
QUOTE {} | Strikingly, abrupt stress increases, rather than cumulative or peak stress magnitude, determine epithelial–mesenchymal transition induction. |