Claim

Model ledger-default@0.1.0 ledger-strict@0.1.0 ledger-default@0.2.0 ledger-strict@0.2.0 ledger-default@0.3.0 (default) ledger-strict@0.3.0 Snapshot seq

Topics

Vaccines · 1efd24fe Medicine · 1efd24fe

Assessment

Why?

Strongest counted support: The phase 1 report says antibody responses remained elevated for at least one year after vaccination. weight 2.000000 evidence

Suppressed as dependent: The excerpt directly states responses increased after the boost and remained elevated for at least one year.

Review gaps: qualifiers reviewed, opposing search done, independence reviewed

What would most change this: One independent, direct measurement that contradicts this claim would move it from Supported to Unresolved.

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Checked as part of

Statements this claim was broken out of. The claim is scored on its own; a statement's reading only counts its claims.

• “A phase 1 trial of the structure-based mRNA-1215 Nipah vaccine in healthy adults reported no serious adverse events and sustained antibody responses through...” · 2 claims · 29 September 2026

Evidence for

• The phase 1 report says antibody responses remained elevated for at least one year after vaccination.

  From A structure-based mRNA vaccine for Nipah virus in healthy adults: a phase 1 trial Read 2026-09-29 Relevance DIRECT Steps 0 Counted

  Primary phase 1 immunogenicity follow-up.

• The excerpt directly states responses increased after the boost and remained elevated for at least one year.

  From A structure-based mRNA vaccine for Nipah virus in healthy adults: a phase 1 trial Read 2026-09-29 Relevance DIRECT Steps 0 Counted

Evidence against

None.

Qualifications

None.

Suppressed as dependent

Evidence	Group	Kept instead
6db3b48a		cfdb6137

Inferences

Concluded from

None.

Used as a premise in

None.

An inference is interpretation, not evidence: it never changes the assessment of its conclusion. Each premise is a claim with its own evidence.

Threads

None. Threads are for disagreements about how a determination was made — a statement whose figures are not in the passage it rests on, two sources that may share an origin. Something about the world belongs in the evidence above.

Claim edges

None. Edges are stored and displayed; v0.1 does not propagate probability across them.

Review checklist

Review checks: 1 of 4

2 checks by this claim's own author, alongside the independent review above. 1 QUALIFIER CHECK · 1 EVIDENCE VERIFICATION. A check by the person who recorded a claim does not raise its review coverage.

Check	Done	By
qualifiers reviewed	no
opposing search done	no
independence reviewed	no
primary source reviewed	yes	1bfdd8c0, cfdb6137

Summary

Contribution history

seq	event	detail
18299	APPENDED
18300	ACCEPT	AUTOMATIC_AFTER_VALIDATION
18309	LINK_EVIDENCE	by 1efd24fe (accepted)
24698	TASK_RESULT	by 1efd24fe (accepted)

Score trace

{
  "claim": "0b3df062-5667-8b4f-8b8a-9122bcfadece",
  "links": [
    {
      "kept": "b7e343ae-ef18-8841-9a9f-6eafcfdb6137",
      "link": "2a4c5b74-8e23-8aaa-a7e5-8d511bfdd8c0",
      "group": null,
      "reason": "dependent_strongest_only",
      "edition": "NAMED_OR_UNRELATED",
      "evidence": "b05e8dd3-a90a-8ab4-b702-7dae6db3b48a",
      "direction": "SUPPORT",
      "magnitude": "1.800000",
      "relevance": "DIRECT",
      "extraction": "UNVERIFIED",
      "provenance": "INDEPENDENT",
      "observation": "DIRECT_TEXT",
      "source_type": "PRIMARY_TEXT",
      "authenticity": "UNVERIFIED",
      "audit_confirmed": false,
      "effective_weight": "0.000000",
      "interpretive_steps": 0
    },
    {
      "link": "b7e343ae-ef18-8841-9a9f-6eafcfdb6137",
      "group": null,
      "edition": "NAMED_OR_UNRELATED",
      "evidence": "c871a330-cd54-86f2-9e8d-6c3e7b60b3a6",
      "direction": "SUPPORT",
      "magnitude": "2.000000",
      "relevance": "DIRECT",
      "extraction": "UNVERIFIED",
      "provenance": "INDEPENDENT",
      "observation": "MEASUREMENT",
      "source_type": "PRIMARY_TEXT",
      "authenticity": "UNVERIFIED",
      "audit_confirmed": false,
      "effective_weight": "2.000000",
      "interpretive_steps": 0
    }
  ],
  "model": "ledger-default@0.3.0",
  "prior": "0.50",
  "variants": {
    "spread": "0.1287",
    "permissive": "0.9309",
    "conservative": "0.8022"
  },
  "code_hash": "sha256:c61a6fdf35a754a0d7e958df149036a083c0eaeb7d2d2e52704ec32b0c36def7",
  "contested": false,
  "stability": "MEDIUM",
  "claim_type": "QUANTITATIVE",
  "config_hash": "sha256:86768038080b8ab5233f1e4b7aba10af05b5bb44caa432095150b90e81209809",
  "probability": "0.8808",
  "provisional": true,
  "evidence_sum": "2.000000",
  "snapshot_seq": 25852,
  "prior_log_odds": "0.000000",
  "support_groups": 1,
  "model_dependent": false,
  "review_coverage": "0.25",
  "truth_evaluable": true,
  "assessment_state": "SUPPORTED",
  "review_checklist": {
    "qualifiers_reviewed": {
      "by": [],
      "ok": false
    },
    "opposing_search_done": {
      "by": [],
      "ok": false
    },
    "independence_reviewed": {
      "by": [],
      "ok": false
    },
    "primary_source_reviewed": {
      "by": [
        "2a4c5b74-8e23-8aaa-a7e5-8d511bfdd8c0",
        "b7e343ae-ef18-8841-9a9f-6eafcfdb6137"
      ],
      "ok": true
    }
  },
  "contradict_groups": 0,
  "rounding_boundary": false,
  "posterior_log_odds": "2.000000",
  "not_applicable_reason": null,
  "independence_unreviewed": 2
}