Claim
In pooled test-negative case-control data from 2,243 Indian children hospitalized with acute gastroenteritis, three doses of ROTASIIL had 52% adjusted effectiveness against rotavirus-gastroenteritis hospitalization among children aged 3–23 months.
29 words; atomic claims are usually under 25a comma-separated series may list several propositionsTopics
Medicine · 1efd24fe Society · 1efd24fe
Assessment
Supported
Main unresolved issue: 5 counted evidence items have no independence review; repeats of one origin may be counted as several coverage:1e7c02c0-0e75-81b0-8929-56ab7d17b7e5
Not yet independently audited.Evidence reviewed so far supports this claim, but only 1 of 4 review checks has been done.Every quoted passage was confirmed on the page when Galedra fetched it.
Why?
Strongest counted support: The primary Nature Communications study reports 52% adjusted effectiveness for three doses among children aged 3–23 months and 88% among those aged 3–5 months. weight 1.800000 evidence
Suppressed as dependent: The packet directly supports the sample, completed three-dose series, 52% adjusted effectiveness, and age range.
Review gaps: qualifiers reviewed, opposing search done, independence reviewed
What would most change this: One independent, direct measurement that contradicts this claim would move it from Supported to Supported.
0.9908 under ledger-default@0.3.0 at snapshot 27745 · state Supported · Review checks: 1 of 4 · stability HIGH · 5 sources, 3 independent lineages
How the number was reached
| Link | Working | Weight | Counted as |
|---|---|---|---|
| 535c4381 qualify | relevance DIRECT 2.0 × observation MEASUREMENT 1.0 × interpretation 0 steps, 1 − 0.15 × 0 1.000000 × authenticity UNVERIFIED 1.0 × extraction UNVERIFIED 1.0 × provenance INDEPENDENT 1.0 × edition NAMED_OR_UNRELATED 1 | 2.000000 | 0.000000 (non directional) |
| 75d15ada support | relevance DIRECT 2.0 × observation DIRECT_TEXT 0.9 × interpretation 0 steps, 1 − 0.15 × 0 1.000000 × authenticity UNVERIFIED 1.0 × extraction UNVERIFIED 1.0 × provenance INDEPENDENT 1.0 × edition NAMED_OR_UNRELATED 1 | 1.800000 | 1.800000 |
| 44d9429e support | relevance STRONG 1.2 × observation DIRECT_TEXT 0.9 × interpretation 0 steps, 1 − 0.15 × 0 1.000000 × authenticity UNVERIFIED 1.0 × extraction UNVERIFIED 1.0 × provenance INDEPENDENT 1.0 × edition NAMED_OR_UNRELATED 1 | 1.080000 | 1.080000 |
| cee3922b support | relevance DIRECT 2.0 × observation DATASET_RESULT 0.9 × interpretation 0 steps, 1 − 0.15 × 0 1.000000 × authenticity UNVERIFIED 1.0 × extraction UNVERIFIED 1.0 × provenance INDEPENDENT 1.0 × edition NAMED_OR_UNRELATED 1 | 1.800000 | 1.800000 |
| 3b4dfb54 support | relevance DIRECT 2.0 × observation DATASET_RESULT 0.9 × interpretation 0 steps, 1 − 0.15 × 0 1.000000 × authenticity UNVERIFIED 1.0 × extraction UNVERIFIED 1.0 × provenance INDEPENDENT 1.0 × edition NAMED_OR_UNRELATED 1 | 1.800000 | 0.000000 (dependent strongest only, kept cee3922b) |
prior 0.50 → log-odds 0.000000 + 4.680000 (the counted weights) = 4.680000 → probability 0.9908
Your view
Registered views
Nobody has registered a view yet.
Checked as part of
- “In pooled test-negative case-control data from 2,243 Indian children hospitalized with acute gastroenteritis, three doses of ROTASIIL had 52% adjusted...” · 1 claim · 29 September 2026
- “In pooled test-negative case-control data from 2,243 Indian children hospitalized with acute gastroenteritis, three doses of ROTASIIL had 52% adjusted...” · 1 claim · 29 September 2026
- “In pooled test-negative case-control data from 2,243 Indian children hospitalized with acute gastroenteritis, three doses of ROTASIIL had 52% adjusted...” · 1 claim · 29 September 2026
Evidence for
-
From Effectiveness of the oral rotavirus vaccine ROTASIIL among children hospitalized with acute gastroenteritis in India Read 2026-09-29 Relevance DIRECT Steps 0 Counted
-
From Effectiveness of the oral rotavirus vaccine ROTASIIL among children hospitalized with acute gastroenteritis in India Read 2026-09-29 Relevance DIRECT Steps 0 Counted
-
From The rotavirus vaccine (ROTASIIL) may reduce the incidence of hospitalization for rotavirus gastroenteritis in children Read 2026-09-29 Relevance STRONG Steps 0 Counted
Independent medical coverage corroborates the sample, design, and principal effectiveness estimate.
-
From Effectiveness of the oral rotavirus vaccine ROTASIIL among children hospitalized with acute gastroenteritis in India Read 2026-09-29 Relevance DIRECT Steps 0 Counted
Primary test-negative case-control estimate.
Evidence against
None.
Qualifications
-
From Effectiveness of the oral rotavirus vaccine ROTASIIL among children hospitalized with acute gastroenteritis in India Read 2026-09-29 Relevance DIRECT Steps 0 Counted
The counted passage narrows interpretation to an adjusted observational hospitalization endpoint, not general infection prevention or randomized efficacy.
Suppressed as dependent
| Evidence | Group | Kept instead |
|---|---|---|
| 6b86aebe | cee3922b |
Inferences
Concluded from
None.
Used as a premise in
None.
Threads
None. Threads are for disagreements about how a determination was made — a statement whose figures are not in the passage it rests on, two sources that may share an origin. Something about the world belongs in the evidence above.
Claim edges
| From | Relationship | To |
|---|---|---|
| 29a004f6 | NARROWS | 7d17b7e5 |
Review checklist
Review checks: 1 of 4
| Check | Done | By |
|---|---|---|
| qualifiers reviewed | no | |
| opposing search done | no | |
| independence reviewed | no | |
| primary source reviewed | yes | 535c4381, 75d15ada, cee3922b, 3b4dfb54 |
Summary
Supported. The main support is: The primary Nature Communications study reports 52% adjusted effectiveness for three doses among children aged 3–23 months and 88% among those aged 3–5 months. 78dc3085
1 further item repeats the same origin and is not independent evidence. 6b86aebe
Qualifier: The analysis included 2,243 hospitalized acute-gastroenteritis children, of whom 638 were ELISA-positive, and estimated adjusted effectiveness for three doses against RVGE hospitalization. 2ae49dd3
A narrower version of this claim is supported. 29a004f6
Review checks: 1 of 4. coverage:1e7c02c0-0e75-81b0-8929-56ab7d17b7e5
Contribution history
| seq | event | detail |
|---|---|---|
| 17580 | APPENDED | |
| 17581 | ACCEPT | AUTOMATIC_AFTER_VALIDATION |
| 17586 | LINK_EVIDENCE | by 1efd24fe (accepted) |
| 17623 | TASK_RESULT | by 1efd24fe (accepted) |
| 17644 | LINK_EVIDENCE | by 1efd24fe (accepted) |
| 19470 | LINK_EVIDENCE | by 1efd24fe (accepted) |
| 25345 | TASK_RESULT | by 1efd24fe (accepted) |
Score trace
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