Claim
In the reported randomized crossover trial, seven-day N-acetylcysteine supplementation did not change 60-minute time-trial distance in trained men or women.
Topics
Nutrition · 1efd24fe Sports · 1efd24fe
Assessment
Supported
Main unresolved issue: 2 counted evidence items have no independence review; repeats of one origin may be counted as several coverage:dc7846b4-903c-868f-8b62-17ce7c3a24a4
Not yet independently audited.Evidence reviewed so far supports this claim, but only 1 of 4 review checks has been done.Every quoted passage was confirmed on the page when Galedra fetched it.
Why?
Strongest counted support: The abstract reports no change in 60-minute time-trial distance after NAC in either sex. weight 2.000000 evidence
Suppressed as dependent: The excerpt directly reports no change in 60-minute time-trial distance after NAC in both male and female participants.
Review gaps: qualifiers reviewed, opposing search done, independence reviewed
What would most change this: One independent, direct measurement that contradicts this claim would move it from Supported to Unresolved.
0.8808 under ledger-default@0.3.0 at snapshot 27745 · state Supported · Review checks: 1 of 4 · stability MEDIUM · 2 sources, 1 independent lineage
How the number was reached
| Link | Working | Weight | Counted as |
|---|---|---|---|
| 83db1377 support | relevance DIRECT 2.0 × observation MEASUREMENT 1.0 × interpretation 0 steps, 1 − 0.15 × 0 1.000000 × authenticity UNVERIFIED 1.0 × extraction UNVERIFIED 1.0 × provenance INDEPENDENT 1.0 × edition NAMED_OR_UNRELATED 1 | 2.000000 | 0.000000 (dependent strongest only, kept c947faf4) |
| c947faf4 support | relevance DIRECT 2.0 × observation MEASUREMENT 1.0 × interpretation 0 steps, 1 − 0.15 × 0 1.000000 × authenticity UNVERIFIED 1.0 × extraction UNVERIFIED 1.0 × provenance INDEPENDENT 1.0 × edition NAMED_OR_UNRELATED 1 | 2.000000 | 2.000000 |
prior 0.50 → log-odds 0.000000 + 2.000000 (the counted weights) = 2.000000 → probability 0.8808
Your view
Registered views
Nobody has registered a view yet.
Checked as part of
- “In a randomized double-blind crossover trial of trained endurance adults, seven-day NAC supplementation did not change 60-minute time-trial distance but...” · 2 claims · 29 September 2026
Evidence for
-
From The effect of acute NAC supplementation on sport performance outcomes may depend on sex and genetic polymorphism in trained endurance adults: a randomized clinical trial Read 2026-09-29 Relevance DIRECT Steps 0 Counted
The trial abstract directly reports the null time-trial distance result.
-
From The effect of acute NAC supplementation on sport performance outcomes may depend on sex and genetic polymorphism in trained endurance adults: a randomized clinical trial Read 2026-09-29 Relevance DIRECT Steps 0 Counted
The passage explicitly states the null result in both sexes.
Evidence against
None.
Qualifications
None.
Suppressed as dependent
| Evidence | Group | Kept instead |
|---|---|---|
| a2fc7730 | c947faf4 |
Inferences
Concluded from
None.
Used as a premise in
None.
Threads
None. Threads are for disagreements about how a determination was made — a statement whose figures are not in the passage it rests on, two sources that may share an origin. Something about the world belongs in the evidence above.
Claim edges
None. Edges are stored and displayed; v0.1 does not propagate probability across them.
Review checklist
Review checks: 1 of 4
| Check | Done | By |
|---|---|---|
| qualifiers reviewed | no | |
| opposing search done | no | |
| independence reviewed | no | |
| primary source reviewed | yes | 83db1377, c947faf4 |
Summary
Supported. The main support is: The abstract reports no change in 60-minute time-trial distance after NAC in either sex. 6cc82a57
1 further item repeats the same origin and is not independent evidence. a2fc7730
Review checks: 1 of 4. coverage:dc7846b4-903c-868f-8b62-17ce7c3a24a4
Contribution history
| seq | event | detail |
|---|---|---|
| 15473 | APPENDED | |
| 15474 | ACCEPT | AUTOMATIC_AFTER_VALIDATION |
| 15485 | LINK_EVIDENCE | by 1efd24fe (accepted) |
| 15489 | TASK_RESULT | by 1efd24fe (accepted) |
Score trace
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"model": "ledger-default@0.3.0",
"prior": "0.50",
"variants": {
"spread": "0.1287",
"permissive": "0.9309",
"conservative": "0.8022"
},
"code_hash": "sha256:c61a6fdf35a754a0d7e958df149036a083c0eaeb7d2d2e52704ec32b0c36def7",
"contested": false,
"stability": "MEDIUM",
"claim_type": "COMPARATIVE",
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"review_coverage": "0.25",
"truth_evaluable": true,
"assessment_state": "SUPPORTED",
"review_checklist": {
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},
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}
},
"contradict_groups": 0,
"rounding_boundary": false,
"posterior_log_odds": "2.000000",
"not_applicable_reason": null,
"independence_unreviewed": 2
}