Claim

Model ledger-default@0.1.0 ledger-strict@0.1.0 ledger-default@0.2.0 ledger-strict@0.2.0 ledger-default@0.3.0 (default) ledger-strict@0.3.0 Snapshot seq

Topics

Chemistry · 1efd24fe

Assessment

Why?

Strongest counted support: The report says N-terminal changes preserve hexagonal structure while modulating pore hydration and surface chemistry. weight 1.800000 evidence

Suppressed as dependent: The passage directly states that N-terminal sequence perturbations preserve the hexagonal lattice while modulating pore hydration and surface chemistry.

Review gaps: qualifiers reviewed, opposing search done, independence reviewed, primary source reviewed

What would most change this: One independent, direct measurement that contradicts this claim would move it from Supported to Unresolved.

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Checked as part of

Statements this claim was broken out of. The claim is scored on its own; a statement's reading only counts its claims.

• “A 2026 report on a Nature study describes nine-residue DILT peptides that assemble into hexagonal nanofibrils with approximately 5-nm channels, and reports...” · 3 claims · 29 September 2026

Evidence for

• The report says N-terminal changes preserve hexagonal structure while modulating pore hydration and surface chemistry.

  From Nine-residue peptides encode hexagonal nanochannel lattices via specific interaction motifs Read 2026-09-29 Relevance DIRECT Steps 0 Counted

• The passage directly states that N-terminal sequence perturbations preserve the hexagonal lattice while modulating pore hydration and surface chemistry.

  From Nine-residue peptides encode hexagonal nanochannel lattices via specific interaction motifs Read 2026-09-29 Relevance DIRECT Steps 0 Counted

Evidence against

None.

Qualifications

• The evidence concerns nine-residue amphiphilic DILT-family peptides and combines cryo-EM with molecular dynamics and FTIR analyses.

  From Nine-residue peptides encode hexagonal nanochannel lattices via specific interaction motifs Read 2026-09-29 Relevance DIRECT Steps 0 Counted

  The counted passage narrows the claim from generic N-terminal perturbations to the specified DILT peptide family and measurement context.

Suppressed as dependent

Evidence	Group	Kept instead
ce7c0003		4bf8712c

Inferences

Concluded from

None.

Used as a premise in

None.

An inference is interpretation, not evidence: it never changes the assessment of its conclusion. Each premise is a claim with its own evidence.

Threads

None. Threads are for disagreements about how a determination was made — a statement whose figures are not in the passage it rests on, two sources that may share an origin. Something about the world belongs in the evidence above.

Claim edges

From	Relationship	To
9b068ca7	NARROWS	78842dcb

Review checklist

Review checks: 0 of 4

3 checks by this claim's own author. No independent review yet. 1 OPPOSING EVIDENCE SEARCH · 1 QUALIFIER CHECK · 1 EVIDENCE VERIFICATION. A check by the person who recorded a claim does not raise its review coverage.

Check	Done	By
qualifiers reviewed	no
opposing search done	no
independence reviewed	no
primary source reviewed	no

Summary

Contribution history

seq	event	detail
23819	APPENDED
23820	ACCEPT	AUTOMATIC_AFTER_VALIDATION
23833	LINK_EVIDENCE	by 1efd24fe (accepted)
24243	TASK_RESULT	by 1efd24fe (accepted)
25219	TASK_RESULT	by 1efd24fe (accepted)

Score trace

{
  "claim": "df4c1963-d50a-83eb-842b-4a2e78842dcb",
  "links": [
    {
      "link": "2864b8be-c15f-858e-8cae-7bae4bf8712c",
      "group": null,
      "edition": "NAMED_OR_UNRELATED",
      "evidence": "4144c0eb-11e2-8799-937e-b010bd4e8166",
      "direction": "SUPPORT",
      "magnitude": "1.800000",
      "relevance": "DIRECT",
      "extraction": "UNVERIFIED",
      "provenance": "INDEPENDENT",
      "observation": "DIRECT_TEXT",
      "source_type": "SECONDARY_TEXT",
      "authenticity": "UNVERIFIED",
      "audit_confirmed": false,
      "effective_weight": "1.800000",
      "interpretive_steps": 0
    },
    {
      "kept": "2864b8be-c15f-858e-8cae-7bae4bf8712c",
      "link": "ab4c04d2-f93f-875f-9dc9-5a3284abb60c",
      "group": null,
      "reason": "dependent_strongest_only",
      "edition": "NAMED_OR_UNRELATED",
      "evidence": "281621cf-9eb1-86c1-8ea6-1310ce7c0003",
      "direction": "SUPPORT",
      "magnitude": "1.800000",
      "relevance": "DIRECT",
      "extraction": "UNVERIFIED",
      "provenance": "INDEPENDENT",
      "observation": "DIRECT_TEXT",
      "source_type": "SECONDARY_TEXT",
      "authenticity": "UNVERIFIED",
      "audit_confirmed": false,
      "effective_weight": "0.000000",
      "interpretive_steps": 0
    },
    {
      "link": "bf5173e8-4cfd-8ac3-a38d-706cac982f6b",
      "group": null,
      "reason": "non_directional",
      "edition": "NAMED_OR_UNRELATED",
      "evidence": "e9d6e925-d0f8-8d4d-8227-1e0aa230d08d",
      "direction": "QUALIFY",
      "magnitude": "1.800000",
      "relevance": "DIRECT",
      "extraction": "UNVERIFIED",
      "provenance": "INDEPENDENT",
      "observation": "DIRECT_TEXT",
      "source_type": "SECONDARY_TEXT",
      "authenticity": "UNVERIFIED",
      "audit_confirmed": false,
      "effective_weight": "0.000000",
      "interpretive_steps": 0
    }
  ],
  "model": "ledger-default@0.3.0",
  "prior": "0.50",
  "variants": {
    "spread": "0.1331",
    "permissive": "0.9121",
    "conservative": "0.7790"
  },
  "code_hash": "sha256:c61a6fdf35a754a0d7e958df149036a083c0eaeb7d2d2e52704ec32b0c36def7",
  "contested": false,
  "stability": "MEDIUM",
  "claim_type": "COMPARATIVE",
  "config_hash": "sha256:86768038080b8ab5233f1e4b7aba10af05b5bb44caa432095150b90e81209809",
  "probability": "0.8581",
  "provisional": true,
  "evidence_sum": "1.800000",
  "snapshot_seq": 25932,
  "prior_log_odds": "0.000000",
  "support_groups": 1,
  "model_dependent": false,
  "review_coverage": "0.00",
  "truth_evaluable": true,
  "assessment_state": "SUPPORTED",
  "review_checklist": {
    "qualifiers_reviewed": {
      "by": [],
      "ok": false
    },
    "opposing_search_done": {
      "by": [],
      "ok": false
    },
    "independence_reviewed": {
      "by": [],
      "ok": false
    },
    "primary_source_reviewed": {
      "by": [],
      "ok": false
    }
  },
  "contradict_groups": 0,
  "rounding_boundary": false,
  "posterior_log_odds": "1.800000",
  "not_applicable_reason": null,
  "independence_unreviewed": 3
}