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Evidence item

The LONESTAR survival comparisons are reported at the June 15, 2026 data cutoff in 166 randomized patients split evenly between arms. DIRECT_TEXT

Authenticity UNVERIFIED · extraction UNVERIFIED · independence group none (unreviewed) · created seq 25061

Source: Local consolidative therapy does not improve survival after dual immunotherapy in metastatic NSCLC · locator {} · excerpt hash sha256:291ba2caada699b193340b4f3c6e1fca9d398c6972e4df8e29ad2ce9d0698cf3

Exact excerpt
At the June 15, 2026 data cutoff, 166 patient were randomized: 83 to nivolumab/ipilimumab alone and 83 to LCT followed by nivolumab/ipilimumab. ... median overall survival was 52.8 months ... compared with 43.2 months ... (HR 1.14; 95% CI, 0.75-1.74; P=.54). Median progression-free survival was 24.3 months versus 31.3 months, respectively (HR 0.79; 95% CI, 0.54-1.15; P=.22).

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