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Claim

In the randomized phase 3 LONESTAR trial of 166 immunotherapy-naive patients with metastatic non-small-cell lung cancer, adding local consolidative radiation or surgery after nivolumab plus ipilimumab did not significantly improve overall or progression-free survival.

Type QUANTITATIVE · truth-evaluable: yes · status at snapshot: ACTIVE · created seq 19331

34 words; atomic claims are usually under 25a conjunction joins clauses that may be separately evaluable

Referenced 125 times: checked 2, looked up by assistants 0, viewed 84, shared 39. A count of attention, not evidence.

Topics

Medicine · 1efd24fe Health · 1efd24fe

Assessment

Supported

Score: 0.9468 under ledger-default@0.3.0 at snapshot 27745

2 of 4 review checks done · 0 counted · 2 by the author only

2 independent evidence lineages · review checks 0 of 4 · stability HIGH

Main unresolved issue: 4 counted evidence items have no independence review; repeats of one origin may be counted as several coverage:5e38a92d-a174-8abd-8200-eb7f7e7d05e6

Not yet independently audited.Evidence reviewed so far supports this claim, but only 0 of 4 review checks have been done.A quoted passage from cancertherapyadvisor.com was not found on the page when Galedra fetched it.

Why?

Strongest counted support: The report gives the 166-patient randomization and non-significant overall- and progression-free-survival comparisons. weight 1.800000 evidence

Suppressed as dependent: The passage directly reports the 166 randomized patients and non-significant overall- and progression-free-survival comparisons.

Review gaps: qualifiers reviewed, opposing search done, independence reviewed, primary source reviewed

What would most change this: One independent, direct measurement that contradicts this claim would move it from Supported to Leans supported.

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Registered views

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Checked as part of

Statements this claim was broken out of. The claim is scored on its own; a statement's reading only counts its claims.

Evidence for

Evidence against

None.

Qualifications

Suppressed as dependent

EvidenceGroupKept instead
519bdf42676b7a57

Inferences

Concluded from

None.

Used as a premise in

None.

An inference is interpretation, not evidence: it never changes the assessment of its conclusion. Each premise is a claim with its own evidence.

Threads

None. Threads are for disagreements about how a determination was made — a statement whose figures are not in the passage it rests on, two sources that may share an origin. Something about the world belongs in the evidence above.

Claim edges

None. Edges are stored and displayed; v0.1 does not propagate probability across them.

Review checklist

Review checks: 0 of 4

3 checks by this claim's own author. No independent review yet. 1 OPPOSING EVIDENCE SEARCH · 1 QUALIFIER CHECK · 1 EVIDENCE VERIFICATION. A check by the person who recorded a claim does not raise its review coverage.

CheckDoneBy
qualifiers reviewedno
opposing search doneno
independence reviewedno
primary source reviewedno

Summary

Supported. The main support is: Independent oncology coverage confirms the 166-patient LONESTAR randomization and non-significant overall- and progression-free-survival results, including the reported hazard ratios. e8d696bb

1 further item repeats the same origin and is not independent evidence. 519bdf42

Qualifier: The LONESTAR survival comparisons are reported at the June 15, 2026 data cutoff in 166 randomized patients split evenly between arms. b5c5f1ba

A search for evidence in the opposing direction found none. 6c5575ad

Review checks: 0 of 4. coverage:5e38a92d-a174-8abd-8200-eb7f7e7d05e6

Generated by stub-v0.1; every sentence cites graph ids.

Contribution history

seqeventdetail
19331APPENDED
19332ACCEPTAUTOMATIC_AFTER_VALIDATION
19337LINK_EVIDENCEby 1efd24fe (accepted)
19339TASK_RESULTby 1efd24fe (accepted)
19381LINK_EVIDENCEby 1efd24fe (accepted)
25061TASK_RESULTby 1efd24fe (accepted)