Evidence item

The result is restricted to embryonic weeks 6–11 and 56 atlas-defined cell states; trait links combine association/inference with mouse validation rather than universal human causal tracing. DATASET_RESULT

Authenticity UNVERIFIED · extraction UNVERIFIED · independence group none (unreviewed) · created seq 25733

Source: Atlas of cell types and regulatory elements underlying human facial diversity · locator {} · excerpt hash sha256:c0f4ad138a0b750b6ed380b27d88fffc55d1b149b8ad5f59e23f5940ebf4a7f6

Exact excerpt

The multimodal atlas covers human embryonic weeks 6–11 and characterizes 56 cell states using single-cell transcriptomics, chromatin accessibility and spatial transcriptomics. Gene-expression associations with facial traits were strongest in early mesenchymal progenitors and became more region restricted. The study used GWAS inference, cell-signalling analysis and mouse validation; it does not establish that every association is causal in humans.

Linked claims

Claim	Direction	Relevance	Steps	Counted
5e199669	QUALIFY	DIRECT	0	yes

Audits

None.