Evidence item
The authors say their data cannot resolve active displacement versus recruitment kinetics, competitive binding, or membrane-environment changes. DIRECT_TEXT
Source: TRAM promotes Toll-like receptor-free myddosome signal transduction: supplementary reviewer response · locator {} · excerpt hash sha256:6944819a74490c4349e497e147898dec410b8f4f97923adb468f5a9680cb9123
Exact excerpt
The precise molecular mechanism driving the apparent displacement of TIRAP and enrichment of TRAM during this transition is not directly addressed by our current study. Our data do not yet allow us to resolve whether this reflects active displacement, differential recruitment kinetics, competitive binding, or changes in local membrane microenvironments.
Linked claims
| Claim | Direction | Relevance | Steps | Counted |
|---|---|---|---|---|
| 94edb4c0 | CONTRADICT | MODERATE | 0 | yes |
Audits
None.