Evidence item

The primary abstract reports state-of-the-art performance across coding and non-coding human variant-effect tasks. DIRECT_TEXT

Authenticity UNVERIFIED · extraction UNVERIFIED · independence group none (unreviewed) · created seq 22395

Source: Predicting genome-wide functional constraints with GPN-Star · locator {} · excerpt hash sha256:669665af1a19a7d4d16b889756f5a2a852608ebfd6e61e6fa0948a62dee3c794

Trained on alignments spanning vertebrate, mammal and primate evolutionary timescales, GPN-Star achieves state-of-the-art performance across a wide range of variant effect prediction tasks in both coding and non-coding regions of the human genome.