Evidence item

The results report 32 Wnt-enhanced elements, 7 vehicle-enhanced elements, and 12 condition-dependent allelic variants. MEASUREMENT

Authenticity UNVERIFIED · extraction UNVERIFIED · independence group none (unreviewed) · created seq 14821

Source: Massively parallel assessment of gene regulatory activity at human cortical-structure-associated variants · locator {} · excerpt hash sha256:d4de41c1b74c61a9701c6af82212d0f043efb1b39a4dd884321c185eb32997d0

Exact excerpt

We found 32 elements with higher activity because of Wnt stimulation and seven elements with higher activity in the vehicle condition, demonstrating Wnt-dependent gene regulation of cortical-structure-associated elements. ... By using an interaction test, we detected 12 variants with allelic effects that differ significantly across conditions (condition-dependent emVars; FDR < 0.1).

Linked claims

Claim	Direction	Relevance	Steps	Counted
584a4cab	SUPPORT	DIRECT	0	yes

Audits

None.