Evidence item

A secondary report corroborates that microbial adhesion activates Piezo1 in myeloid cells as an initiating mechanical signal for innate immunity. DIRECT_TEXT

Authenticity UNVERIFIED · extraction UNVERIFIED · independence group none (unreviewed) · created seq 20083

Source: How Microbial Adhesion Switches On Piezo1 to Launch Innate Immunity · locator {} · excerpt hash sha256:c9e603953d9e3c689012f173e92062d67d5083bd031406ecf7201218382a5320

The central discovery of the work is that microbial adhesion to myeloid cells activates Piezo1, a mechanosensitive ion channel that converts mechanical forces into cellular signals.