Evidence item

The dataset abstract limits the atlas to human cranial meninges at 6–21 post-conception weeks and phrases yolk-sac origin as support from multiomic data. DIRECT_TEXT

Authenticity UNVERIFIED · extraction UNVERIFIED · independence group none (unreviewed) · created seq 25721

Source: Spatially resolved multiomics of human meninges development reveal lineage and disease dynamics – AnnData objects · locator {} · excerpt hash sha256:e8aa9c84ed7f75931755dd7e7e93b9cf946dd7cbdf3bb1c140743b891e9699e0

Exact excerpt

Here we constructed a paired single-nuclei RNA and ATAC atlas of human meningeal development from 6–21 post-conception weeks across cranial regions. By integrating spatial transcriptomics, we resolved cell types across meningeal layers. Within immune compartments, the data support a yolk-sac origin for meningeal myeloid lineages, including perivascular macrophages primed for barrier immunity.

Linked claims

Claim	Direction	Relevance	Steps	Counted
def9e18a	QUALIFY	DIRECT	0	yes

Audits

None.