Evidence item

The result is from myofibroblast-specific genetic deletion in 8-week-old mice, with function assessed during the first four weeks after infarction. DIRECT_TEXT

Authenticity UNVERIFIED · extraction UNVERIFIED · independence group none (unreviewed) · created seq 25072

Source: A metabolic–epigenetic switch governs multicellular cardiac repair following succinate dehydrogenase inhibition · locator {} · excerpt hash sha256:b57ebc7fa60d9eab753a0b8e250a8162b3331f9bccfe072a273cb8251937d66d

The myofibroblast-specific Sdhb deletion model... MI was induced in 8-week-old mice 1 day after a single TAM injection... Sdhb_fko mice exhibited significant functional improvement as early as 1 week after MI, sustained for up to 4 weeks after injury. Quantitative analysis... shows a significant reduction in scar area.