Evidence item

The primary trial reports a time-specific reduction estimate with a confidence interval crossing zero and attenuation during the inter-epidemic period. DIRECT_TEXT

Authenticity UNVERIFIED · extraction UNVERIFIED · independence group none (unreviewed) · created seq 25871

Source: Impact of Wolbachia-mediated incompatible and sterile insect techniques on dengue incidence: a large-scale cluster randomised controlled trial · locator {} · excerpt hash sha256:af46838b5ca05a84fee9846ae0ef9f0ec74eefd6afbac6e5fd4d20a9a184b7f5

Six months after releases began, intervention clusters showed reductions in total dengue incidence, ranging from 27.6% (95% CI: −35.4% to 61.3%) to 83.8% (95% CI: 50.4%–94.7%). This protective effect varied across time, with some attenuation observed during the 2023 inter-epidemic period.