Evidence item

The passage directly reports the calibrated 0–15 kPa measurement range and use in tumour spheroids and mouse xenografts. DIRECT_TEXT

Authenticity UNVERIFIED · extraction UNVERIFIED · independence group none (unreviewed) · created seq 21225

Source: Mechanical stress remodelling drives epithelial–mesenchymal transition in the tumour microenvironment · locator {} · excerpt hash sha256:e2fbf18620e43a72a4c18b2d53125a08ca036ccd1361a154332e86702d56df6d

Calibration of the stress–R2 relationship enables a quantitative measurement of local tissue stress over a physiologically relevant range of 0–15 kPa. We demonstrate the platform in tumour spheroids and mouse xenografts, enabling the non-invasive, spatiotemporal mapping of tissue stress during tumour progression.