Evidence item

The primary study reports identification of a protein-coding chimeric transcript in mice. DIRECT_TEXT

Authenticity UNVERIFIED · extraction UNVERIFIED · independence group none (unreviewed) · created seq 21598

Source: Functional chimeric mRNAs encode proteins in mammalian immunity · locator {} · excerpt hash sha256:5b50deda2cbad6e09b0e58dc3de95313d7ffb793a070790952d3a2a52ee91e95

We identify a protein-coding chimeric mRNA representing a fusion between the pore-forming protein gasdermin D (GSDMD) and a C-terminal domain translated out of frame from Tmem106a (Gsdmd-Tmem106a) in mice.